Pituitary adenomas from basic research to diagnosis and therapy : proceedings of the 6th European Workshop on Pituitary Adenomas, Berlin, Germany, 24-27 July, 1996 by European Workshop on Pituitary Adenomas (6th 1996 Berlin, Germany)

Cover of: Pituitary adenomas | European Workshop on Pituitary Adenomas (6th 1996 Berlin, Germany)

Published by Elsevier in Amsterdam, New York .

Written in English

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Subjects:

  • Pituitary gland -- Cancer -- Congresses.,
  • Adenoma -- Congresses.,
  • Pituitary Neoplasms -- congresses.,
  • Adenoma -- congresses.

Edition Notes

Includes bibliographical references and index.

Book details

Statementeditors, Klaus von Werder, Rudolf Fahlbusch.
SeriesInternational congress series ;, no. 1126
ContributionsWerder, Klaus von., Fahlbusch, Rudolf.
Classifications
LC ClassificationsRC280.P5 E86 1996
The Physical Object
Paginationx, 346 p. :
Number of Pages346
ID Numbers
Open LibraryOL1007819M
ISBN 100444824251
LC Control Number96047748

Download Pituitary adenomas

The idea for this book developed as an outcome of a multidisciplinary sym­ posium entitled "Pituitary Adenoma Update" that was held at Tufts-New En­ gland Medical Center in April /5(1). Pituitary adenomas are a heterogeneous group of tumors with distinctive secretory and growth characteristics, and the molecular pathophysiology of sporadic adenomas is mostly unclear.

Approximately 5% of pituitary adenomas occur in the setting of an inherited or familial condition and these tumors may exhibit more aggressive characteristics.

Pituitary adenomas are tumors of the anterior pituitary. Most pituitary tumors are slow-growing and benign. They are classified based on size or cell of origin. Pituitary adenoma can be described as microadenoma, macroadenoma, and giant tumors based on size. Microadenoma is tumors less than 10 mm, while macroadenoma includes tumors larger than 10mm.

By agreement with the publisher, this book is accessible by the search feature, but cannot be browsed.

Holland-Frei Cancer Medicine. 6th edition. Show details. Search term. GH-Secreting Pituitary Adenomas. Chirag D. Gandhi, MD and Kalmon D. Post, MD. Growth hormone secretion is under hypothalamic control via somatostatin and growth hormone Author: Chirag D. Gandhi, Kalmon D.

Post. The third edition will continue to be divided into sections that summarize normal hypothalamic-pituitary development and function, hypothalamic-pituitary failure, and pituitary tumors; additional sections will describe pituitary disease in systemic disorders and diagnostic procedures, including imaging, assessment of the eyes, and biochemical testing.

Brain MRI (with and without gadolinium, cone-down sella turcica) - preferred. Test Sensitivity: % (for sella turcica mass); Test Specificity: % (for sella turcica mass); Also obtain if MRI not contraindicated and Pituitary Adenoma inicidentally found on CT Head; Repeat Brain MRI in months depending on lesion size.

About Pituitary Adenomas. Pituitary adenomas arise from the pituitary gland and are by far the most common growth associated with the gland; they account for 15% of primary brain tumors and are the third most common intracranial tumor after meningiomas and great majority (over 90%) of pituitary adenomas are benign slow growing tumors, approximately % are.

Overview Pituitary gland = master gland Located at the base of the brain It balances hormones made by most glands Link between the brain and the endocrine system Anterior 80% of gland produces hormone Somatotropin or GH- Growth hormone Thyrotropin or TSH- Thyroid stimulating hormone Corticotrophin or ACTH- Adrenocorticotropic hormone Gonadotropins or FHS, LH- Follicle [ ].

Pituitary adenomas are benign tumors of the pituitary gland. Most are located in the anterior lobe (front portion) of the gland. About 1 in 10 people will develop a pituitary adenoma in their lifetime. Some pituitary adenomas secrete one or more hormones in excess. Even when they are small in size.

Eminent clinicians and specialists thoroughly review in great detail every aspect of pituitary tumors. The topics covered include prolactinomas, somatotroph adenomas, corticotroph adenomas, thyrotroph adenomas, nonfunctioning tumors, pituitary tumors, invasive adenomas, and pituitary carcinomas, as well as lesions, exclusive of pituitary adenomas, that occur in the sellar region.

a pituitary adenoma is either partial or complete hypo-pituitarism, most often hypogonadism. This is a result of interference with normal hormone secretion, either. Description The Pituitary, Fourth Edition, continues the tradition of a cogent blend of basic science and clinical medicine which has been the successful hallmark of prior editions.

This comprehensive text is devoted to the pathogenesis, diagnosis, and treatment of pituitary disorders. Which of the following is true of pituitary adenoma. Most pituitary carcinomas are hormonally inactive tumors. Most pituitary adenomas are part of hereditary or familial syndromes.

The diagnosis of pituitary carcinoma is based on presence of cerebrospinal fluid or systemic metastases. Diabetes insipidus is often associated with adenoma.

Transsphenoidal surgical resection is the first-line therapy for most pituitary adenomas; however, non-secretory microadenomas generally only require follow-up, and prolactin-producing pituitary adenomas (prolactinomas) are best treated with dopamine agonists (e.g., bromocriptine, cabergoline).

About this book. Introduction. The idea for this book developed as an outcome of a multidisciplinary sym­ posium entitled "Pituitary Adenoma Update" that was held at Tufts-New En­ gland Medical Center in April The purpose of that symposium was to put together our current knowledge of the cause of pituitary tumors and discuss the diagnostic evaluation and management that was now appropriate.

Pituitary adenomas are primary tumors that occur in the pituitary gland and are one of the most common intracranial neoplasms. Depending on their size they are broadly classified into: pituitary microadenoma: less than 10 mm in size; pituitary macroadenoma: greater than 10 mm in size; Although this distinction is largely arbitrary, it is commonly used and does highlight an important fact.

pituitary tumor is pituitary adenoma — adeno means gland, oma means tumor. Most pituitary adenomas develop in the front two-thirds of the pituitary gland. That area is called the adenohypophysis, or the anterior pituitary.

Pituitary tumors rarely develop in the rear one-third of the pituitary gland, calledFile Size: 1MB. Pituitary adenomas are almost always benign and slow-growing although with time they can locally invade adjacent structures.

In general, these tumors remain well-circumscribed and contain well-differentiated cells which almost never undergo metastasis. WHO classification of pituitary adenomas was revised in The two major and significant changes are discussed.

(1) The new classification focuses on adenohypophysial-cell lineage for the. Pituitary Neoplasms () Definition (MEDLINEPLUS) Your pituitary gland is a pea-sized gland at the base of your brain. The pituitary is the "master control gland" - it makes hormones that affect growth and the functions of other glands in the body.

Abstract Pituitary adenomas (PAs) are common, benign intracranial tumors that are usually effectively controlled with surgery, pharmacotherapy or radiotherapy.

Some PAs against which conventional treatment is ineffective are great clinical challenges at present. Autophagy is a widespread physiological process in : Zhebao Wu, Weiting Gu. It is the intention of Pituitary Adenoma: Pathophysiology, Diagnosis and Treatment Options to illustrate the current scientific results regarding the pathogenesis and progression of this neoplasm and also to explain in every detail the diverse diagnostic and therapeutic modalities used nowadays.

Nova publishes a wide array of books and. On average, patients who use Zocdoc can search for a doctor for Pituitary Adenoma, book an appointment, and see the doctor within 24 hours. Same-day appointments are often available, you can search for real-time availability of doctors for Pituitary Adenoma in your area who accept your insurance and make an appointment online.

Common endocrine symptoms. Hypopituitarism—pituitary macroadenomas (adenomas >1 cm) can be associated with hormone hyposecretion due to progressive compression of the normal pituitary gland cells.5 Growth hormone deficiency is most common and can cause a wide variety of non-specific symptoms including fatigue and weight gain ().Gonadotrophin deficiency is also common and.

Endocrine Inactive, FSH, LH and A-SU Adenoma: Clinical Findings and Endocrinology. TSH Adenoma: Clinical Findings, Endocrinology and Treatment. Neuroophthalmologic Findings in Pituitary Adenomas. Radiology of Pituitary Adenomas.

Inferior Petrosal Sinus Sampling: Technique and Results. Positron Emission Tomography (PET) in Pituitary Adenomas. Pituitary adenoma. New York: Plenum Medical Book Co., © (OCoLC) Online version: Pituitary adenoma.

New York: Plenum Medical Book Co., © Introduction.- 2. Insights into The Pathogenesis of Adenoma Based on Embryological Considerations.- 3. Pituitary Adenomas Arising Due to Prolonged Hormonal Stimulation or Loss of Normal.

The management of pituitary adenomas and other sellar tumors is one of the most difficult tasks for neurosurgeons and endocrinologists. Optimal treatment requires a multidisciplinary approach; neurological, ophthalmological, and endocrinological tests are all required.

Fortunately, the past decade has seen rapid improvements in the management of patients with pituitary adenomas and other. Not all pituitary tumors (called pituitary adenomas) cause symptoms. But when they do, they can cause many different types of symptoms.

The first signs of a pituitary adenoma often depend on whether the tumor is functional (making excess hormones) or non-functional (not making excess hormones). Functional adenomas can cause problems because of the hormones they release. Sometimes, pituitary adenomas are found by accident when an MRI or CT is being done for another condition.

*An MRI uses a large magnet, radio waves, and a computer to create clear images of the body. CT uses computers to combine many X-ray images into cross-sectional views of the inside of the body. Do et al. retrospectively analyzed 61 patients with recurrent or residual pituitary adenomas who underwent endoscopic endonasal surgery and found that the gross total resection was achieved in 31 patients (%), indicating that endoscopic endonasal approach is a safe and effective option for recurrent pituitary adenomas.

This issue of Neurosurgery Clinics Guest Edited by Drs. Manish K. Aghi and Lewis S. Blevins will focus on Pituitary Adenoma.

Topics include but are not limited to Molecular biology of nonfunctional and functional pituitary adenomas Intraoperative Fluorescent Visualization of pituitary adenomas Intraoperative MRI for pituitary adenomas Pituitary Apoplexy Management of giant pituitary adenomas.

With pituitary adenomas, cortisol secretion is increased over the baseline. High-dose dexamethasone suppression confirms diagnosis of a pituitary adenoma.

It suppresses the pituitary gland even in the presence of an adenoma. If cortisol levels remain unchanged, the cause of increased cortisol is not a pituitary adenoma. Since the early work of Minkowski, who attributed acromegaly to a pituitary tumor (Minkowski ), neoplasms composed of pituitary adenohypophysial cells have been recognized as the cause of significant r, Harvey Cushing attributed the term ‘adenoma’ even to patients who died of their disease (Cushing ).We now recognize that these neoplasms are complex and.

pituitary adenomas and to explore the clinical relevance of the findings. METHODS. The authors conducted a metaanalysis of all existing English-language articles in MEDLINE.

They used the search string (pituitary adenoma or pituitary tumor) and prevalence and selected relevant autopsy and imaging evaluation studies for inclusion. RESULTS. Pituitary adenomas are primary tumours that occur in the pituitary gland and are one of the most common intracranial neoplasms.

Depending on their size they are broadly classified into: pituitary microadenoma: less than 10 mm in size; pituitary macroadenoma: greater than 10 mm in size; Although this distinction is largely arbitrary, it is commonly used and does highlight an important fact.

P ediatric pituitary adenomas (PPAs) are rare neoplasms that account for 2% of all pediatric brain tumors. 32 Typical clinical presentation depends on the extent of mass effect and, for secreting tumors, which trophic hormones are dysregulated.

In addition to headaches, children frequently come to medical attention because of visual disturbances, growth failure, or abnormal pubertal onset. Pituitary adenomas are the third most common intra-cranial neoplasms in adults, accounting for about 10% of all intra-cranial tumours.

Surawicz TS, McCarthy BJ, Kupelian V, et al. Descriptive epidemiology of primary brain and CNS tumors: results from the Central Brain Tumor Registry of. Recently, a number of novel genetic alterations have been identified that predispose individuals to pituitary adenomas. Clinically relevant pituitary adenomas are relatively common, present in % of the general population.

They are mostly benign monoclonal neoplasms that arise from any of the five hormone-secreting cell types of the anterior lobe of the pituitary gland, and cause disease due. More than 95 percent of all cases of acromegaly are the result of a growth hormone–secreting pituitary adenoma.

Growth hormone–secreting pituitary adenomas begin in the somatotropic cells of the pituitary gland. Also called GH, the growth hormone secreted by these tumors triggers the liver to produce insulin-like growth factor 1, or IGF Read More about pituitary disorders types, symptoms, causes, prevention and treatment.

A group of hormonal disorder that results from a chemical imbalance caused due to derangement or poor functioning of the pituitary gland. Read More about pituitary disorders types.

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